Research Interests

Bardet-Biedl Syndrome, Primary cilia, ciliogenesis, retinal degeneration, obesity

Dr. Hernandez investigates the molecular mechanisms of genetic disorders, specializing in ciliopathies like Bardet-Biedl syndrome (BBS). He develops animal models to study disease pathogenesis and validate the preclinical efficacy of gene therapies. His research on AAV-based delivery systems has led to multiple patents and the co-founding of Axovia Therapeutics Ltd. As CSO of this UCL spin-out based at Brunel, he leads the development of first-in-human gene therapies for inherited retinal and neurometabolic disorders.